CC-115 - CAS# 1228013-15-7 Catalog No.:M6483-10 also known as NCGC00242364 and

also known as NCGC00242364 and ANTAG3

(2007) Cancer Res

Chemical Name: 4-oxo-1

Curr Hematol Malig Rep

CC-115 - CAS# 1228013-15-7 Catalog No.:M6483-10 also known as NCGC00242364 andCC 115, CAS No. 1228013 15 7, is a dual inhibitor of DNA dependent protein kinase (DNA PK) and mammalian target of rapamycin (mTOR), with potential antineoplastic activity. CC 115 binds to and inhibits the activity of DNA PK and both raptor mTOR (TOR complex 1 or TORC1) and rictor mTOR (TOR complex 2 or TORC2), which may lead to a reduction in cellular proliferation of cancer cells expressing DNA PK and TOR. DNA PK, a serine threonine kinase and a