α-Guanidinoglutaric Acid rulline Exposure of cells to Genz-123346

Exposure of cells to Genz-123346 and to other GCS inhibitors at non-toxic concentrations can enhance the killing of tumor cells by cytotoxic anti-cancer agents

+1/p-1/b10-9+

Formula: C7H16N2O2

STAT5-IN-2 is a STAT5 inhibitor

α-Guanidinoglutaric Acid rulline Exposure of cells to Genz-123346Guanidinoglutaric Acid is a novel nitric oxide synthase inhibitor with Ki value of 2. 69 M . In the brain, nitric oxide (NO), which is synthesized from L arginine (Arg) by NO synthase (NOS), acts as both an intra and an intercellular second messenger, and it may suppress convulsions . Guanidinoglutaric Acid (GGA) is a novel nitric oxide synthase inhibitor. GGA was increased in the cobalt induced epileptic focus tissue in the cerebral cortex of cats .